College students with Autism Spectrum Disorder (ASD) experience unique challenges and difficulties within the academic and social realms they interact in. Fifteen college students with ASD enrolled in the BUILD program at the University of Indianapolis participated in programming for 13 weeks. Baseline data from the Autism Social Skills Profile-2 and survey results gathered from students were the foundation for the program and curriculum design to ensure relevance to students. Following 13 weeks of a multi-setting intervention program, students more consistently demonstrated the use of appropriate social skills in a variety of settings. Students also self-reported improved confidence with their ability to utilize social and life skills in real world scenarios. With their improved confidence and clear ability to engage more appropriately with others, students are more capable of succeeding in academic, social, independent living, and work-related settings.