Studies conducted on the integument of amphibians within Plethodontidae revealed these salamanders have mucous, granular, and modified composite multicellular glands in their skins. Unfortunately, few species have been studied to date. Thus, the purpose of this study was to investigate the histological diversity of the integumentary glands found on the ventral and dorsal surfaces of the Zigzag Salamander, Plethodon dorsalis, and compare these features to those found on the Northern Two-Lined Salamander, Eurycea bislineata, and the Cave Salamander, Eurycea lucifuga. These three species are found in the same family, Plethodontidae, which is comprised of more than 250 species. The data was then used to form a preliminary comparative study that investigated the histological diversity of integumentary glands found on the ventral and dorsal surfaces of terrestrial adult lungless salamanders. Results showed that P. dorsalis had polarization to its two skin surfaces, with mucous glands dominating ventrally and poison glands dominating dorsally. Additionally, P. dorsalis had similar morphology to their glands as that observed in other lungless salamanders with the distinction of the stratum corneum lining the ducts of both poison and mucous glands in a valve like manner.