Health literacy is a large component of a patient’s understanding of educational healthcare materials. Because educational materials in healthcare are usually written at relatively high literacy levels, they are inaccessible to the individuals who need it most: the patients and their caregivers. By limiting the accessibility of this information, it can impact the quality of life and level of independence patients have in the future. During this project, a program called Readable was utilized to improve current best practices and existing documents for individuals with amyotrophic lateral sclerosis (ALS). Individuals with ALS and former caregivers were interviewed in order to create optimal resource guides and improve the accessibility of information for the Les Turner ALS Foundation. Through interviews, it was discovered that tone, word choice, and the amount of information presented were all vital to the approachability and comprehension of healthcare material. The importance of how new healthcare documents were presented was also discovered. In this case, individuals with ALS and former caregivers felt the sooner materials were provided, the better. While Readable indicated that literacy levels of documents had decreased by an average of 1.27 grade levels, participants also deemed the resource guides approachable and easy to read. This information is important so that organizations can improve their educational materials and ensure a broad audience has access to new and critical health-based information.