Background. COVID-19 has impacted the healthcare system, including the occupational therapy profession. Occupational therapy practitioners have had to adapt to these unknown times to best treat their clients. The conditions of COVID-19 have caused moral distress in practitioners. Purpose. The purpose of this study was to explore moral distress within the lived experiences of OT practitioners during the time of COVID-19. Method. Investigators utilized a stratified-purposeful sample to select occupational therapists in a variety of settings. Investigators conducted a semi-structured interview to explore their experience with moral distress during the time of COVID-19. The data were analyzed using a hermeneutical phenomenological approach to generate themes regarding the experience of moral distress. Findings. Investigators were able to identify commonalities in various settings as the COVID-19 Pandemic impacted occupational therapy practitioners. These commonalities helped the investigators determine that the themes of the study were COVID-19, moral distress (MD) in OT, experiences, stressors, OT practitioner role, uncharted waters, managing moral distress, effects, personal protective equipment (PPE), COVID impact on roles, encouragement, mental health, vaccine impact, employment complications, and therapeutic relationships. Discussion. This study’s findings brought awareness to the experience of OT practitioners during the pandemic and explored implications for preparing OT practitioners for future occurrences of moral distress. Keywords: COVID-19; ethics; mental health; moral distress