The Pediatric Outcomes Data Collection Instrument (PODCI) is a self-reported outcome measure designed to assess upper extremity function and pain in adolescents. The purpose of this study was to determine the test-retest reliability and concurrent validity of the upper extremity function and pain portions of the PODCI (PODCI UEF and PODCI P) as an outcome measure in adolescents diagnosed with joint hypermobility (JH). The study also sought to establish the responsiveness of the PODCI subscales by calculating the standard error of measurement (SEM) and the minimal detectable change (MDC). One hundred and fifty adolescents (ages 11-18 years) with JH were recruited for the study. Test-retest reliability of both portions of the PODCI was examined with 83 participants using Lin’s concordance correlation coefficient (ƿc) There was a very high test-retest reliability for the PODCI UEF, ρc = .81 (p < .001) and moderate test-retest reliability for the PODCI P, ρc = .68 (p < .001). To establish concurrent validity, the PODCI UEF was compared to the Patient Reported Outcomes Measurement Information System Pediatric Upper Extremity-Short Form (PROMIS PUE-SF) and the PODCI P was compared to Numeric Rating Scale (NRS) using Spearman rho correlations. There was a very high correlation between the PODCI UEF and the PROMIS PUE-SF, rs = .80 (p < .001) and a moderate inverse relationship rs = -.73 (p < .001) between PODCI P and NRS scores. These results, indicate concurrent validity between instruments. Occupational and physical therapists may consider using the PODCI clinically and in future research.