Occupational therapy practitioners treating patients with UE conditions use various patient-reported outcome measures to evaluate patients’ function throughout care. FOTO for the UE has limited research to support its use in OT, yet CMS endorses FOTO as a means to measure value-based reimbursement. The purpose of this study was to further explore the utility of FOTO as a functional outcome measure used with patients with orthopedic UE injuries receiving OT services. Using a multiple regression model, researchers found that FOTO intake score, duration of therapy, and injury location were significant predictors of FOTO discharge scores. The number of visits was not a significant predictor. An ANCOVA determined a statistically significant difference in discharge scores among injury locations when controlling for FOTO intake scores. Researchers performed a post hoc analysis with a Bonferroni adjustment showing only one statistically significant mean difference between wrist and hand, indicating that patients with hand injuries tend to have more dysfunction at therapy discharge than wrist injuries. While FOTO does have some advantages as a valid and reliable tool for patients with UE injuries, continued research is indicated to further define the utility of FOTO by OT practitioners.