Adolescents with a congenital hand or upper extremity (CHUE) anomaly who underwent surgical correction at an early age may be sensitive to psychosocial well-being during a vulnerable period of development. As a dominant amount of literature focuses on improving and maintaining functional capacity after surgery, it is also necessary to understand psychosocial factors (PSFs) that may contribute to long-term treatment outcomes. The purpose of this study was to explore PSFs of body appreciation, self-esteem, and resilience within a population of adolescents with a surgically corrected CHUE anomaly; ascertain if these factors are influenced by gender, age, or extremity involvement; and determine what variables may predict resilience in the population. Using a non-experimental, analytic cross-sectional study design at a tertiary pediatric orthopedic institution, a total of 31 participants responded to a survey incorporating the Body Appreciation Scale-2 (BAS-2), the Rosenberg Self-Esteem Scale (RSES), and the Child and Youth Resilience Measure (CYRM-R). Statistical significance (p = .011) was found for RSES scores between young (10-13 year-old) and old (14-19 year-old) adolescents. Correlation coefficients were greater than .30 for both BAS-2 and RSES scores when compared to CYRM-R scores. Multiple regression analysis resulted in a model that explained 44.3% of the variance, with a linear predictive model of F(2, 25) = 9.96, p < .001; R2 = .44. Patients who appreciate and find value regarding their anomaly are speculated to have greater resilience and therefore more favorable long-term outcomes.